Scientist I

Piper Companies is seeking a Scientist I to join a growing pharmaceutical organization in Greenville, SC. The Scientist I will be heavily focused on analytical sample preparation, extraction techniques, and method validation activities supporting raw material and finished product testing in a cGMP-regulated lab. This role is centered around complex sample matrices, HPLC analysis, validation documentation, and pharmaceutical lab compliance.

Responsibilities of the Scientist I:

• Perform hands-on analytical sample preparation and extraction of target analytes from complex raw material and finished-product matrices utilizing dilution, filtration, centrifugation, and multi-step extraction techniques.

• Evaluate extraction efficiency, sample recovery, dilution requirements, and matrix interference while supporting method verification and validation studies.

• Author, execute, and summarize method verification and validation protocols and reports in accordance with USP <1225>, USP <1226>, and ICH Q2(R2) guidelines.

• Conduct HPLC analysis utilizing Empower chromatography software to generate, review, and report analytical data while troubleshooting sample preparation and analytical issues.

• Maintain complete cGMP documentation including lab notebooks, data review, protocol execution, and adherence to approved SOPs and data integrity requirements.

• Support analytical testing of raw materials, in-process samples, and finished products while participating in method transfers and lab investigations as needed.

Qualifications of the Scientist I:

• BS or MS in Chemistry or related scientific discipline with 4+ years of pharmaceutical laboratory experience.

• Extensive hands-on experience with analytical sample preparation, extraction procedures, recovery studies, and troubleshooting matrix-related analytical challenges.

• Proven experience performing and documenting method verifications, method validations, and method transfers within a cGMP environment.

• Advanced proficiency with HPLC chromatography and Empower software; experience with Agilent HPLC systems is preferred.

• Strong understanding of FDA-regulated laboratory operations, cGMP requirements, and data integrity principles.

• Comprehensive knowledge of USP <1225>, USP <1226>, ICH Q2(R2), and pharmaceutical analytical testing requirements.

Compensation for the Scientist I includes:

• Compensation Depending on Experience

• Comprehensive benefits package including medical, dental, vision, and retirement plans

• Around 6 Month Contract

This job opens for applications on 10/07/2026. Applications for this job will be accepted for at least 30 days from the posting date.

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